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2) AWA is activated upon addition of bz and AWB is activated upon removal of bz (at the medium concentration).
Such types of intermediates were first suggested by Cram[ 25] and subsequently observed by Olah and co-workers.[ 26] Accordingly, our plausible mechanism involves silver-activated addition of the iodane to the double bond of [D2]- 2 a to give the iodonium ion 6. Togni and co-workers[ 27] studied the activation of the CF3 analogue of 1 using zinc salts.
Further investigation into the cAMP-dependent mechanism led to an interesting observation which described ATF-1 activation by LPS-stimulated macrophages whereas CREB was not activated; the addition of VIP abrogated this activation.
All the nucleoside analogs must be activated by addition of a phosphate group before they have antiviral activity.
The SPDP-HSA was activated by addition of DTT, which results in the formation of a thiol-activated protein.
Transcription of the gene array can be activated by addition of glucocorticoid hormone, which induces nuclear translocation of GR for gene activation.
We found that phosphodiesterase on unilluminated disc membranes can indeed be fully activated by addition of T alpha containing bound p[NH]ppG.
In acetone, ratiometric channel was activated upon addition of n-Bu4NF, and more than 50 nm red shift from 590 nm to 641 nm was obtained and accompanied with emission color from orange to purple red.
Acyclovir, similar to all other nucleoside analogs, must be activated by addition of a phosphate group (phosphorylation) before it can inhibit the synthesis of viral DNA (HSV and VZV are DNA viruses).
3HP is then activated by addition of coenzyme A by Pct.
PGR and CCND1 were activated by addition of E2 independently of the type of medium.
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