The phrase "activate the pathway" is correct and usable in written English.
It can be used in contexts related to biology, technology, or processes where a specific route or method is being initiated or engaged.
Example: "To begin the experiment, we need to activate the pathway that leads to the desired chemical reaction."
Alternatives: "initiate the pathway" or "trigger the pathway."
This amount increased but activity decreased insulin failed to activate the pathway.
Alternatively, PIK3CA mutations might only moderately activate the pathway and/or constitutive activity of mutant PIK3CA may induce negative feedback loops that preclude a more pronounced activation of the pathway [ 14].
Our work suggests that both kinase-active and kinase-impaired CFC alleles are effectively gain-of-function mutations and activate the pathway because combinations of active and impaired BRAF mutant alleles can promote an additive effect during early development (Fig. 4).
To activate the pathway in neurons, we expressed the constitutively active HEP (hepCA) with the elavGal4 driver.
Cross talk between erb-1 and ER has been shown to activate the pathway, which has been associated with oestrogen-independent transcriptional activity (Aronica and Katzellenbogen, 1991; Pietras et al, 1995; Smith, 1998; Campbell et al, 2001), and breast cancer cell lines with activated Akt is resistant to the growth inhibitory effects of Tamoxifen (Degrafenried et al, 2002).
In contrast, in HEK 293 or NIH 3T3 cells Dkk2 will inhibit a Wnt-Fz signal but activate the pathway, when cotransfected with Lrp5 or -6 (Wu et al., 2000; Li et al., 2002; Mao and Niehrs, 2003).
The oxidative environment is pivotal in the formation of aromatics to activate the pathways involving the resonantly stabilized radicals in the aromatic growth process.
(a) Wnt forms a ternary complex with Fz and Lrp6, which promotes stabilization of β-catenin, thereby activating the pathway.
Overexpression of Rheb activates the pathway independent of Tsc gene function [11] [13].
Increased signalling via the epidermal growth factor family (ERBB) receptors also activates the pathway.
The exact mechanism by which N-cadherin activates the pathway remains to be elucidated.
