Our results showed that BZcon1 was directly involved in activating the development of conidiophores, because the BZcon1 mutants lost the conidia production capacity.
This result suggested that BA treatment activates the development of arrested pistil primordia in male flowers by repressing the expression of the TS2 homolog in J. curcas, which resulted in an increase in the ratio of female to male flowers.
RANKL activates the development of pre-osteoclasts to become mature osteoclasts, while osteoprotegerin or OPG serves as a secreted receptor of RANKL (decoy receptor), resulting in inhibition of RANKL binding to its cell surface receptor and activation of osteoclast maturation.
In addition, ectopic expression of Scr, Antp, and Ubx in early and late appendage buds may activate the leg development program, leading to leg-like transformation of head appendages.
In the case of CVD, circulating inflammatory mediators may activate the vascular endothelium, enhancing the development of atherosclerosis (reviewed in Seymour et al. [ 2]).
This crosstalk can occur at a number of levels, including the type-1 tyrosine kinase growth factor family (epidermal growth factor receptor and HER2) [ 32] and the PI3K/Akt pathway [ 33] interacting directly to activate ER signalling, with evidence that these pathways become upregulated or activated during the development of endocrine resistance [ 34].
Using the Gene- Switch line allows us to activate the RNA-hairpin construct after development has finished, minimizing pleiotropic results.
Our results are consistent with those of Jammes et al. [ 38], who found genes encoding pectin esterases and pectate lyases were activated in Arabidopsis thaliana roots after infection with Meloidogyne incognita and the cell wall loosening process was activated during the development of the giant cell as well.
Once the endothelium becomes activated during the development of sepsis, it transforms into a procoagulant, antifibrinolytic, and proadhesive state [12].
