The phrase "activate the alternative" is correct and usable in written English.
It can be used in contexts where you want to initiate or enable a different option or choice, often in technical or decision-making scenarios.
Example: "To proceed with the backup plan, we need to activate the alternative that was discussed in the meeting."
Alternatives: "enable the alternative" or "turn on the alternative".
Masp1 has been shown to activate the alternative pathway18 and even to directly cleave C3 (ref. 19).
Because antibodies are not needed to activate the alternative pathway but are required to set off the classical cascade the alternative pathway serves as a first defense against infection and is part of the nonspecific, innate immune response, which occurs before a specific, acquired immune response can be mounted.
To verify if these strains activate the alternative pathway, C3b deposition was analyzed in serum treated with EGTA to chelate Ca2+.
It may indirectly activate the alternative pathway as a consequence of activating the classic pathway [ 41, 44, 45].
It has been speculated that accumulation of ICs involving GPI may activate the alternative complement pathway to cause inflammatory arthritis [ 16].
Of note, monoclonal λ light chains from a patient with DDD have been reported to activate the alternative pathway directly through an interaction with CFH.
Similarly, posttranslational modification of p100 by SUMO is a determining factor for stimuli-induced p100 processing, which is the primary step in activating the alternative NF- κB, and blocking SUMOylation of p100 would inhibit ultimate activation of the alternative NF- κB pathway [ 37].
It is noteworthy that strains 8612, Y and Gamba 05 activated the alternative pathway less than the other strains analyzed.
The surface of rabbit erythrocytes activated the alternative complement pathway leading to their lysis and release of hemoglobin in the buffer.
However, agonistic TLR9 treatment that activated the alternative nuclear factor-κB pathway increased salivary flow [ 75].
This protein activates the alternative complement pathway thereby strengthening unspecific immune defence mechanisms.
