Although our native microbiota is considerable resilient due to redundancy among its constituent taxa, antibiotic perturbation disrupts our microbial ecosystem and imprints a long-term selection of new community members that possibly deploy or activate species-encoded functional processes.
Although the structure and function of the AhR are highly conserved [ 4], the sensitivity to and the responses elicited by TCDD vary widely across species, suggesting TCDD and related compounds may activate species-specific AhR-mediated gene expression networks.
In particular applying the DBD to generate activated species externally and mix them with the flue gas in a second step is favoured due to its potential energy efficiency and no generation of corrosive acids.
By this, the reaction can only take place when the activating species is present.
Such green activated species were suppressed in the P3 design, where the linker cytosine was centered in the linker sequence.
For this, the condensation of AMP and glycine was initiated by an organic carbodiimide, the "inorganic" activating agent cyanamide, or the oxyazabenzotriazolide of AMP as the only activating species.
That is, the construction of the models is based purely on qualitative knowledge about a particular regulatory mechanism (e.g., kinase X phosphorylates and activates species Y), without the need to manually enter Boolean expressions (these are created in the background based on the biological data provided [ 69]).
Moreover, the ability of catalysts to activate oxygen species (O*) is strictly necessary for this oxidation reaction.
It is also possible that the ability to activate oxygen species by the CQDs surface played some role.
In the crystal structure of methylornithine synthase, pyrrolysine was found to bind ammonia at the carbon of the imine bond, leading to the hypothesis that the role of this amino acid was to bind and activate methylammonium species toward nucleophilic attack by the Co(I) corrinoid groups of MttC, MtbC, or MtmC.
