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Discover Ludwig'activate receptor' is correct and usable in written English.
You can use it in scientific and technical contexts to refer to an event in which a receptor is turned on. For example, "The drug activated the receptor, causing a cascade of events in the cell."
Exact(11)
Upstream stimuli such as growth factors activate receptor tyrosine kinase, which triggers the activation of phosphoinositide 3-kinase (PI3K) and leads to the generation of PIP3.
Growth factors, such as IGF-1, activate receptor tyrosine kinases leading to the membrane recruitment and activation of the class 1a phosphatidylinositol 3-kinase (PI3K) [15], [15].
For positive allosteric modulator and antagonist candidates test, 5-HT EC20 (0.1 nmol/L) and EC80 (3 nmol/L) were used, respectively, to activate receptor.
The sMHCI might bind to neuronal MHCI receptors in ways that activate receptor signaling, or conversely, prevent the MHCI receptor from binding to membrane-bound MHCI.
With the exception of the S127L mutant, α-MSH was unable to internalize the mutant receptors, suggesting that the ligand fails to fully activate receptor signaling and initiate desensitization and internalization.
These growth factors usually activate receptor tyrosine kinases (RTKs), which in turn activate downstream signaling pathways.
Similar(49)
Dr. Margaret A. Johns, who showed that pheromones can set off hormonal changes in mammals when they activate receptors in a tiny nasal cavity, a process that can attract animals of the opposite sex, died Saturday at St . Vincents Manhattan Hospital.
A common approach is to attach targeting ligands in order to activate receptor-mediated endocytosis.
Wnts are secreted cysteine-rich glycoproteins that act as short-range ligands to locally activate receptor-mediated signalling pathways, and they have been shown to be an essential requirement for normal proliferation and differentiation of the mucosa of the small intestine and colon [35].
Subsequently, type I receptors activate receptor-regulated Smads (R-Smads) through phosphorylation of their two carboxyl-terminal serine residues.
One could speculate that slight, but neither acute nor severe, increases in ROS levels may be sufficient to affect kinases or phosphatases to activate receptor-mediated mitophagy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com