These conditions, however, activate a range of stress response pathways to promote tumor survival and aggressiveness.
Since then, both HIF-1α and HIF-2α were detected in most human cells, and both activate a range of hypoxia response elements with similar efficacy.
Finally, AGEs are able to bind and activate a range of receptors, which then trigger a downstream cascade of pathogenic mediators.
Thus, the lung contains multiple cell types and exposure to LPS is known to activate a range of intracellular and extracellular pathways.
The most important oxygenase is CYP1A2, but also CYP1A1 and CYP1B1 can activate a range of arylamines to reactive intermediates [ 6].
Flagellins from Gram-negative bacteria undergo a direct interaction with the leucine-rich regions in TLR-5 and activate a range of inflammatory cells via a TLR-5-dependent signaling pathway [ 11, 12].
As an alternative, whole detergent-inactivated influenza virus can be combined with ISCOMs, which can deliver enclosed antigen directly to DCs and activate a range of innate cells, generating a TH1 and CTL response [ 84].
This molecule binds to receptor proteins to activate a range of signaling processes that stimulate endothelial cells to become tip cells, and so encourage the formation of new sprouts.
Motivating individuals to modify their behaviours is generally very difficult; therefore, it is important to determine the variables that can help to activate a range of health protective behaviours in order to reduce health risks.
If the hunter is a ranger, then activate the range prayer.
Flat-plate configuration was adopted because a TiO2-coated plate could be easily set up for effective ion implantation treatment to extend the activating spectral range from UV to visible light for a higher solar photonic efficiency.
