Sentence examples for activate period from inspiring English sources

Lack of Mecp2 indeed compromises the sleep-wake cycle in 80% of patients [37] for example owing to the failure to activate Period gene expression and clock entrainment in the hypothalamus [38].

The basic helix-loop-helix-PER-ARNT-SIM (PAS) transcriptional activators BMAL1, CLOCK, and NPAS2 activate the Period (PER1 and PER2) and cryptochrome (CRY1 and CRY2) genes, forming the core components.

Because most treatment associated bleeding deaths occurred in this group of patients, clinicians should maintain platelet counts above 30,000/mmduring the drotrecogin alfa (activated) infusion period [ 12].

Rosenfeld concedes that discontent is not new and did not increase after Ferguson, but he said it gets activated "during periods when we have many heavily publicized and very controversial incidents of police-use of force".

Activating induction periods during the oxidation of cyclopentane are related to the sintering of the metallic phase in reaction conditions.

In the heart, AMPK is activated during periods of cardiac ischaemia [ 5].

For example, HSP27, a chaperone protein that is activated during periods of cellular stress, lies downstream of p38 [49].

The phosphoinositide-3 kinase/Akt pathway appears to be activated during periods of Gln starvation, which may serve as a protective mechanism to limit apoptosis associated with cell stress [ 34].

The pathways involved in respiration are well characterised, flowing from glycolysis to the Krebs cycle, along with well-understood branch points, including the pentose phosphate pathway activated during periods of oxidative stress [ 1] and increased lipid biosynthesis [ 2].

Further considering the role of ER stress in C-6-induced cell death, it is interesting to note that multiple signaling arms of the unfolded protein response (UPR) can be activated during periods of ER stress and interplay between these signaling pathways is directly responsible for the activation of either pro-survival or pro-death pathways (reviewed in [ 39]).

It is assumed that the thermal master switch, which triggers the undifferentiated gonads to follow the male or female pathway, will be the gene(s) that activate the thermosensitive period (TSP) or specify responses during this developmental time window.