Sentence examples for activate pathway from inspiring English sources

The three Hh ligands (Sonic, Indian and Desert) activate pathway signaling by binding to the cell surface receptor Patched (PTCH).

Some of these activate pathway gene sets for antibiotic biosynthesis, and one, adpA, activates some critical aspects of morphological differentiation, at least partially by influencing an extracellular protease cascade [ 8].

Caspase-9 and caspase 3, which are downregulated upon PKB/Akt activation, fail to activate pathways leading to apoptosis [ 19].

Cortical stimulation could variably activate pathways that are part of these networks.

For example, DNA damages activate pathways that involve the genes p53 and Mdm2.

It is likely that, apart from the phosphorylational regulation, Ras could also activate "pathways in cancer" at the transcriptional level.

This suggests that Tpr-Met may activate pathways not engaged by the Tpr-Met Shc or Tpr-Met Grb2 oncoproteins.

For instance, DNA double strand breaks (DSBs) activate pathways that involve the p53 and Mdm2 genes [ 3, 4].

As both receptors activate pathways leading to cell growth, proliferation and differentiation, higher expression at those stages is not surprising.

A non-radiative de-activate pathway is assigned to the non-planar conformation at excited state.

At the transcriptomic level, the MAPK pathway was established as the most prominent activated pathway, which is commonly up-regulated by all PDGFRA and KIT mutants.