The phrase "activate initiation" is not commonly used in written English and may sound awkward or redundant.
It could be used in contexts related to starting a process or system, but it may be clearer to use more standard terminology.
Example: "To begin the project, we need to activate initiation of the new software system."
Alternatives: "start the process" or "trigger the initiation".
Subsequently, mTOR phosphorylates and activates the 70-kDa ribosomal protein S6 kinase (p70S6K), which results in increased translation either directly or indirectly by activating initiation and elongation factors, eIF-2, eIF-4E (through 4E-BP) and eEF-2 (Bodine et al. 2001b; Hornberger et al. 2001) (Suppl. Fig. 2C).
The downstream protein of TRAF2/3 can activate consecutive initiation of MEK4 and MEK7, resulting in the activation of stress-activated protein kinases JNK1/2 [ 29].
In terms of functions, initial data suggested that the small mediator functions to activate transcription initiation in vitro, while the large mediator is inactive or acts as a transcription repressor (Taatjes et al. 2002).
There have been new insights into the molecular mechanisms that regulatory proteins use to sense a given signal and to activate transcription initiation from the cognate promoters.
CCS52A1 encodes an endoreduplication factor, in which mutation could activate trichome initiation [ 13].
GaHOX1 and GaHOX3 with high sequence similarities to GL2 could also activate trichome initiation when expressed in Arabidopsis [ 19].
Choi et al. [ 60] found that in wild-type (WT) and GCD2-homozygous (HO) corneal fibroblast cell lines, melatonin could activate the initiation of autophagy.
Activated translation initiation is essential for the malignant breast cancer phenotype.
This protein binds DNA upstream the −35 box of a promoter and activates transcription initiation of many operons.
Exposure of DiFi cells to mAb 225 activated the initiation caspase-8, which was detectable between 8 and 16 h after exposure of the cells to the antibody.
