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The dynamic nature of NB-LRR localization to different subcellular compartments before and after activation suggests that NB-LRRs may activate immune responses in multiple parts of the cell.
Bacterial/viral CpG DNA and biological active synthetic oligodeoxynucleotides containing an unmethylated CpG motif (CpG ODN) activate immune responses in a toll-like receptor 9 (TLR9 -dependent manner.
Many lmms spontaneously activate immune responses, such as reactive oxygen species (ROS) bursts, callose deposition and the induction of pathogenesis-related (PR) genes (Staskawicz et al. 1995).
Most lmms constitutively activate immune responses, including callose deposition, induction of Pathogenesis related (PR) genes, production of reactive oxygen species (ROS), and accumulation of phytoalexins (Staskawicz et al. 1995).
Furthermore, BAPCs were tested for in vivo delivery of a DNA vaccine previously designed to activate immune responses and capable of controlling tumors induced by type 16 human papilloma virus (HPV-16).
We propose that ER stress resulting from recognition of non-adapted viruses is utilized to discriminate "non-self" at the level of protein processing and to activate immune responses, with unintended consequences on pathogenesis.
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They are recognized as a source of cytokines such as IL-6 or receptor activator for nuclear factor-κ B ligand (RANKL), which activate immune response and osteoclastogenesis [ 2].
Immune rejection is primarily due to hyperacute rejection (HAR) where host antibodies target antigens on the surfaces of the transplanted cells (Krishnamurthy and Gimi, 2011), and sequentially activate immune response to eliminate those cells.
Both class I and II molecules are involved in displaying peptide antigen to host T lymphocytes in order to activate immune response [4].
The antibody contributes to activate immune response against tumor cells exploiting this mechanism of action.
These results demonstrated that influenza A(H1N1) pdm09 virus could be translocated to thymus, and might prime and activate immune response.
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