Sentence examples for activate factors from inspiring English sources

At pharmacological, supraphysiological doses, rFVIIa is able to bind to activated platelets at the site of injury and activate factors IX and X directly, leading to a thrombin burst [ 16].

Tissue factor forms a complex with factor VIIa to activate factors IX and X, thereby initiating the coagulation protease cascades.

Dabigatran acts as a potent anticoagulant by preventing thrombin's conversion of fibrinogen to fibrin and inhibits the ability of thrombin to activate factors V, VIII, and XI.

Once coagulation has been triggered by TF activation, leading to thrombin formation, this can have further procoagulant effects, because thrombin itself can activate factors VIII, IX and X.

Both A-CP and the A-CP-F series hydrogel contain Ca2+ (coagulation factor IV), which would activate factors VII, IX, X, and II (prothrombin) [ 21].

PGC-1α is also known to activate factors, e.g., PPARs, that increase the cellular and organelle uptake, and the catabolic oxidation, of fatty acids (FAO).

Tissue factor serves as a cofactor with factor VII to facilitate the activation of factor X. Alternatively, factor VII can activate factor IX, which, in turn, can activate factor X. Once activated, factor X proceeds to activate prothrombin to thrombin in a reaction requiring factor V. The thrombin converts fibrinogen to fibrin.

Thrombin helps to activate Factor XIII (FXIII) by hydrolyzing the R37-G38 peptide bond.

In the TF-independent mechanism, FVIIa can directly activate factor X on the platelet surface without the presence of TF.

Tissue factors act as cofactor to activate factor X.

It binds to the coagulation factor VIIa to activate factor X, forming a transient ternary complex.