The phrase "activate factor" is correct and usable in written English.
It can be used in contexts where you are referring to initiating or enabling a specific element or component that influences a process or outcome.
Example: "To improve the system's performance, we need to activate the factor that enhances data processing speed."
Alternatives: "enable component" or "trigger element".
The extrinsic pathway begins with the release of tissue factor at the site of vascular damage and leads to the activation of factor X. The route provides an alternative mechanism to activate factor X, from the activation of factor XII.
TFPI activity can be measured by the catalytic activity of the VIIa/TF complex to activate factor X to Xa.
A major mechanism of its hemostatic efficacy is its ability to activate factor X on the surface of activated platelets in a tissue factor (TF -independent manner.
Tissue factor serves as a cofactor with factor VII to facilitate the activation of factor X. Alternatively, factor VII can activate factor IX, which, in turn, can activate factor X. Once activated, factor X proceeds to activate prothrombin to thrombin in a reaction requiring factor V. The thrombin converts fibrinogen to fibrin.
The inhibition of C3b deposition in the alternative pathway could be explained by the direct inhibition of protease D. Protease D is a soluble enzyme, already active in the blood, which has higher specificity to activate factor B, by proteolysis, when it is associated to C3b opsonized to the activator surface or when it is part of the soluble complex B-C3-H2O.
However, most studies agree that monomers fail to activate Factor C.
Tissue factor forms a complex with factor VIIa to activate factors IX and X, thereby initiating the coagulation protease cascades.
High-dose factor VIIa is postulated to act on platelets in the absence of tissue factor to activate factors IX and X and thus enhance thrombin generation.
In addition, the furofuran lignan methyl piperitol (6) possesses platelet activating factor (PAF) antagonist activity [37].
Evidence for platelet-activating factor secretion during immune activation in dogs.
Bazan, H. & Ottino, P. The role of platelet-activating factor in the corneal response to injury.
