The phrase "activate bladder" is correct and usable in written English.
It can be used in contexts related to bodily functions, medical discussions, or discussions about bladder control.
Example: "The doctor explained how certain exercises can help activate the bladder and improve urinary function."
Alternatives: "stimulate the bladder" or "engage the bladder".
Given this downregulation of p21 in tumours compared with high levels of p21 in the single mutant H-Ras and β-catenin activated bladders, we next wished to test the functional importance.
Our finding that the Hh pathway is constitutively activated in bladder tumours raises the possibility of novel therapeutic targets.
Recent studies have identified multiple molecular mechanisms by which the PI3K pathway is activated in bladder tumours.
Survivin mRNA was detected in urine with 94% sensitivity and 95% specificity [ 21], suggesting the survivin promoter is preferentially activated in bladder cancer cells.
We recently demonstrated that androgens activated ELK1 in bladder cancer cells and promoted the proliferation of only ELK1-positive cells and the migration/invasion of both ELK1-positive and ELK1-negative cells [ 33].
In our model the combined deletion of both Lkb1 and Pten in the mouse bladder drastically activates mTOR pathway and this precise activation serves as a signal for EMT program execution (Fig. 6).
Although thrombin is a recognized physiological activator of PAR1 and PAR4, the endogenous enzymes responsible for activating PAR2 in urinary bladder are not known.
We found that the miR-143/145 gene cassette became activated in aorta and bladder at E13.5 (Fig. 3d).
The open circles in Fig. 1 shows the steep dependence of force on MRLC phosphorylation when rabbit urinary bladder was activated with 0.01 100 μM carbachol (these data were previously published [ 11]).
Quantification of p21 levels showed a significant reduction in positivity in the tumours compared with the hyperplastic urothelium of the single HRAS mutant (Supplementary Figure 6, P-value >0.04, Mann–Whitney) and premalignant lesions from mice where β-catenin is activated alone within the bladder.
