Sentence examples for activate an increase in from inspiring English sources

When assayed in the heterologous cell lines, both isoforms activate an increase in intracellular Ca2+ [18], [18] while K3 also stimulates a cAMP increase [16].

In RA, monocyte lineage cells are aberrantly activated: an increase in macrophage infiltration of the synovium promotes inflammation via the production of TNF and other proinflammatory cytokines, and an increase in osteoclast activity promotes erosion of bone [ 19].

Among the genes responding to glucose in strains devoid of PKA some are also controlled by a redundant signalling pathway involving PKA activation, while others are not affected when PKA is activated through an increase in cAMP concentration.

AMPK is allosterically activated by an increase in the cellular AMP ATP ratio which also promotes covalent activation of AMPK (at α-Thr in the activation loop of the catalytic subunit) by upstream AMPKs because binding of AMP to the kinase γ-subunit renders the α-Thr phosphorylation site a poorer substrate for protein phosphatases.

Classically, eNOS is activated through an increase in cytosolic Ca2+ and consequent binding of Ca2+-calmodulin.

Previous evidence has shown that p70S6K was activated by an increase in ROS.

AMPK plays an important role as a cellular energy sensor and is activated by an increase in intracellular adenosine monophosphate (AMP /adenosine triphospha-te (ATP) ratio [ 5].

The column labelled "No glucose added" shows the transcriptional response when PKA is activated through an increase in cAMP that does not involve the presence of glucose [ 5].

For mosquitoes such as Ae. aegypti, host-seeking behavior can be activated by an increase in ambient carbon dioxide (CO2) (Majeed et al., 2014).

Thus far, it has been shown that the eggs of almost all species are activated by an increase in Ca2+ oscillation by spermatozoa during fertilization [ 81, 82].

AMPK is an energy sensor that is activated by an increase in AMP/ATP ratio and directly phosphorylates many metabolic enzymes and therefore plays an important role in glucose uptake, glycogen synthesis, and fat oxidation in skeletal muscle [ 5, 6].