Sentence examples for activate a multitude of from inspiring English sources

The active, ligand-bound ErbB receptors function as homo- or heterodimers, which can activate a multitude of signaling pathways involved in proliferation, differentiation, cell survival, and migration (Normanno et al. 2005).

Subsequently, Gα detaches from Gβγ to create two separate components that can activate a multitude of intracellular signaling pathways e.g., Gα may increase adenylyl cyclase activity, whilst Gβγ can independently act to stimulate phospholipases and MAPK/ERKs, and activate ion channels.

But BMPs and other TGFβ family members also activate a multitude of intracellular signaling pathways in addition to Smads to regulate cell function, including MAP kinases [34], [37], [38].

Upon infection by microbial pathogens, plants activate a multitude of defence responses to combat the attacking intruders [ 1].

Signals of the active (GTP-bound) Ras from the inner plasma membrane (PM) and from endomembranes activate a multitude of effectors including the Raf/MEK/ERK cascade, phosphatidylinositol-3-OH kinases, and Ral-guanine nucleotide exchange factors [5].

JNK1 and p38α/β activate a multitude of AP-1-type transcription factors.

Latent membrane protein 1 acts as a constitutively active member of the tumour necrosis factor receptor family (CD40) (Uchida et al, 1999), activating a multitude of intracellular signalling pathways in a ligand-independent manner.

They are activated by a multitude of different ligands that elicit rapid intracellular responses to regulate cell function.

Severe burn injury activates a multitude of immunologic defense mechanisms, one of these being the massive production of proinflammatory mediators [ 1, 2].

Also, cyclodextrins may activate the extracellular signal-regulated kinase (ERK) pathway; activated phosphorylated ERK has a multitude of targets involved in cell proliferation and survival.

The NLRP3-inflammasome is activated in response to a multitude of pro-inflammatory stimuli, including many pathogen-derived molecules, endogenous inducers of sterile inflammation, and non-pathogen microbial pore-forming toxins, including nigericin and maitotoxin [30], [31], [32], [33], [34], [35].