In summary, the biomarker profile described in this study, i.e., Cathepsin D, miR-146a, ADMA and NT-proBNP seem to support the idea that a circuit of unbalanced oxidative stress, activated Cathepsin D and subsequent cleavage of Prolactin in its 16 kDa form is a driving force for the development of PPCM.
I was activating a subjective circuit of joy and sadness.
If the photon passes through the mirror, it strikes a photoelectric detector, activating a circuit that breaks a vial of poison and kills the cat.
Since pathways work cooperatively, the incorrect activation of a specific circuit can activate a wrong circuit in another pathway creating a perturbed signaling cascade that could eventually result in a disease condition.
In our proposed model, structural cues encoded in a recurrent cortical network in BA47 activate a CSTC circuit to modulate the flow of lexical semantic information from BA45 to an integrated representation of meaning at the sentence level in BA44/6.
During brain development, proper synaptic activity must activate a cascade of genes involved in transforming immature neuronal connections into functional circuits.
For instance, relative to the prediction of a computer's action, forecasting a person's finger movements activated a neural circuit consisting of the MPFC, superior temporal sulcus, and Broca's area [38].
Therefore, retrieval of common and proper nouns might, in principle, differentially activate neurofunctional circuits of memory because of their intrinsic properties (i.e. proper names referring to unique individuals and common nouns being linked more abstract conceptual information).
"They aren't selling just any commodity," says Kessler. "They've designed highly stimulating products, substances that excessively activate the reward circuits of the brain, and consumers come back for more".
Evidently, we can repeat this procedure to test for activating or inhibitory interactions, as well as for all permutations of the circuit (e.g., A activates B or B activates A).
