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Leptin is an adipokine with pleiotropic actions that regulate food intake, energy metabolism, inflammation, and immunity [ 33].
This GH3-mediated auxin homeostasis also was proposed as an essential constituent of auxin actions that regulate stress adaptation responses in plants [ 48].
G-protein-coupled oxytocin receptors (OXTR), however, mediate not only oxytocin peripheral actions in reproduction but also a range of central nervous actions that regulate human social behavior [ 1].
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These results suggest that, besides its established roles, BCAR3 may have additional mechanisms of action that regulate breast cancer aggressive phenotype.
The present study demonstrates that two statins, atorvastatin and simvastatin, inhibited AngII-mediated Smad activation, both in vivo, in rat aorta, and in cultured VSMCs, showing an intracellular mechanism of statins action that regulates vascular fibrosis.
This SNP creates an improved site of action that regulates basal levels of MDM2.
Telmisartan has a PPAR-γ agonist action that regulates carbohydrate and lipid metabolism and also exhibits anti-inflammatory and anti-oxidative effects, thereby ameliorating insulin sensitivity.
In response to such evidence the Institute of Medicine has called for a restriction on the number of tobacco outlets [ 17] while the World Health Organisation recommends national-level action plans that regulate the availability of alcohol [ 2].
However, the identity and molecular actions of negative regulators that regulate the early development of adipocytes remain poorly understood.
This comparison suggests that the effects of ovarian hormones on VMH neurons in rats, given the simple dendritic arbor and short time course for dendrite remodeling, provide a dual opportunity for mechanistic and functional studies that will shed light on i) the neural actions of OT that regulate social behavior and, ii) behaviorally relevant dendrite regulation in a variety of brain structures.
From a set of genes that are downregulated under some experimental conditions, a coordinate action of miRNAs that regulate their expression can be anticipated.
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