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Pancreatic β-cells depolarize in response to glucose and fire calcium-dependent actions potentials that trigger insulin secretion.
The procedure was repeated until actions potentials were no longer evoked by tone stimulation.
Amongst other functions, it is thought that this family of diffuse cytoplasmic proteins provides a 'sink' allowing cells to rapidly buffer intracellular calcium after actions potentials, thus allowing the cell to rapidly repolarise for further firing.
A train of 40 actions potentials (APs) at 83 Hz gave a robust response of 302±50% ΔF/F (n = 12 cells), close to GCaMP2's dynamic range measured in cuvettes [24].
Actions potentials were analyzed offline with Autospike software (v. 4.0, Syntech).
Stimulating C2 to fire a train of actions potentials (10 Hz for 2 s) induced a burst of action potentials in VSI in 47 out of 53 preparations with PdN6 intact.
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Could this cause release without action potentials?
CT assessment of motor unit action potentials.
simulation will undergo action potentials during a stimulation pulse.
Lecture 18 (April 4): Neuron biology: axons, dendrites, synapses, action potentials.
I. Enhancement of compound action potentials to masked tones.
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