Sentence examples for actionable targets for from inspiring English sources

This case suggests that molecular profiling may give us better understanding of genetic changes in mucosal melanoma and may afford actionable targets for therapy.

Identification of the largest gaps in EBDM competencies within a state or locality provides health department leaders with actionable targets for the improvement of EBDM capacity.

More work is warranted to shed light on the role of this metabolic axis in cancer because of its potential as an actionable target for treatment [ 110, 111].

Given its centrality for many cancer types, this apical master controller is currently used as clinically actionable target for anti-cancer therapies [ 40].

To determine immediate actionable targets from our previous chemosensitivity screen, we have identified RIP2 as a gene important for breast cancer cell metastasis.

This represents a critical first step towards individualized cancer treatment since it provides a reproducible approach in reporting actionable targets and allows for a quick turnaround time for real-time treatment of patients.

Identifying imaging biomarkers of genotype and phenotype of cancer is the ultimate goal for oncological imagers as well as oncologists because this information can provide actionable targets without the need for tissue sampling.

Improvements in sequencing technologies have evolved into new paradigms for analyzing tumor specimens; massively parallel screens can examine patient samples for potentially actionable targets.

This analysis highlights additional actionable targets [ 50] that may prove effective for the treatment of some brain metastasis, such as PI3 kinase inhibitors.

The difficulty in defining gene copy number as a predictive biomarker for stratification of patients for targeted therapy is well recognized even with established actionable targets, such as HER2 in breast cancer.

To date, there have been significant barriers to this approach: the amount of time necessary for genomic profiling, the ability to identify actionable targets, the availability of therapies to act on those targets, and the need for rebiopsy.