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114, 115 Having thus extended Lashley's hypothesis to a specific neural circuit, we turn to Lashley's final hypothesis: that the capacity to process musical and linguistic hierarchical sequences is unusually developed in humans, but builds upon and extends preexisting action sequencing mechanisms present in animals.
In particular, the PCS included the cingulo-insular SN, an aspect of the attention and monitoring of the priority of stimuli processing and fronto-parietal CEN linked to working memory, planning, execution and action sequencing and the orbitofrontal areas related to reward, motivation and goal driven behaviour [22].
The most prominent additions to this Broca-centered action sequencing capacity were, by hypothesis, those two great human achievements: music and language.
Thus, although intriguing, these results do not support the strong inferences some draw about a specific role of Broca's area in this task, 35 which involves action sequencing but not hierarchical sequencing per se.
Benefits from AChEIs have also been demonstrated for executive deficits (action sequencing, response inhibition and verbal fluency) visuospatial tasks (the Clock Drawing Test) and hallucinations (Emre et al., 2004; Litvinenko et al., 2008).
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CEO of Professional Science Editing for Scientists @ prosciediting.com