According to Bunge, theories in technology come in two types: substantive theories, which provide knowledge about the object of action, and operative theories, which are concerned with action itself.
Haji also shares with Fischer and Ravizza a mechanism-based reasons-responsive approach that holds fixed in analysis the springs of action actually operative in bringing about a freely willed action (1998, pp. 65-85).
Further studies will be required in bladder cancer to determine if similar or alternate mechanisms of action are operative.
As noted by Schlatter et al. (1996), if a direct genotoxic mechanism of action were operative, one would expect a CBI in excess of 1,000.
Although different mechanisms of action are operative, some VDA are tubulin-interactive small molecules that selectively inhibit microtubule polymerisation in endothelial cells (Tozer et al, 2008; Schwartz, 2009).
For kidney carcinogenicity, the U.S. EPA (2011d) concluded that a mutagenic mode of action is operative for TCE, providing further biological plausibility for the epidemiologic findings of TCE-induced kidney cancer.
New insights, using various forms of small non-coding RNAs, suggest that a mechanism of action is operative in human cells, which utilizes non-coding RNAs to direct epigenetic marks to homology containing loci resulting ultimately in the epigenetic-based modulation of gene transcription.
As part of the action, Russian operatives will be expelled from the US, and two Russian compounds in New York and Maryland used for "intelligence-related purposes" will be closed.
The results from Fig. 3 underscore a spatially dependent least-action principle operative for water that is not hydrogen bonded to the protein.
Is it possible, then, that the notion of "information" may be less misleading than that of design in theology's inevitable reflections on how divine purposive action could be operative in the natural world?..
