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These include cancer, Alzheimer's disease, Parkinson's disease and the complications of type-2 diabetes (nephropathy, cataracts, stroke and pain), which might all benefit from knowledge of carnosine's mode of action on human cells.
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Thus, the present study was developed to investigate the action of the triterpene lupane 3 β, 6 β, 16 β-trihydroxylup-20(29 -ene isolated from C. leprosum flowers on human topoisomerases, as well as its effect on human cells, in order to contribute with the knowledge about the mechanism of action of lupane on human PBMC function.
Each is tested on human cells.
To further prove the involvement of mPRα in P4's action on human BPBC cells, the mPRα-expressing plasmid DNA was introduced into the parent MB231 cells and then treated by P4 as indicated.
Similarly, vitamin C proved to have cytotoxic action on human cancer cells and induce apoptosis [ 47].
To obtain proof-of-principle for CNF1 action on human glioma cells, two surgical specimens were obtained from patients with GBM (WHO grade IV).
C.S., C.M. and I.A. performed experiments on human cell lines.
One of them KW-13 showed potent inhibitory activity against bacteria without hemolytic action on human blood red cells.
We aimed to evaluate the direct antitumor effect and elucidate the potential mechanism of Bisebromoamide actions on human RCC cells.
The aim of this study was to evaluate the effect and elucidate the potential mechanism of Bisebromoamide actions on human RCC cells.
We demonstrated that hyperthermia at 42°C, termed heat shock, suppressed the gene expression and production of vascular endothelial growth factor in human fibrosarcoma HT-1080 cells and inhibited its in vitro angiogenic action on human umbilical vein endothelial cells.
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