Higher levels of recombination allow for the efficient action of selection thereby targeting reductions of genetic polymorphism to the selected locus, whereas low levels of recombination subject neighboring polymorphisms to the effects of background selection or genetic hitchhiking.
Moreover, the action of selection will simultaneously affect both the distribution of T and Λ about the selected site(s).
Do some natural populations have low slope because of the action of selection on them?
Few studies have investigated the action of selection at the molecular level during island adaptive radiations [6], [7].
Second, the action of selection in highly expressed genes is preferentially directed toward sequences outside the regions coding for functional domains.
In the effort to minimize the cost of gene transcription, the action of selection should preferentially be directed toward distal introns.
It is known that negative and balancing selection tends to decrease FST in a locus-specific manner, whereas local positive selection tends to increase FST [82], although unusual FST values are not a definitive proof of the action of selection.
Any single mortality distribution exposed significantly more often to the action of selection will be moved towards older ages faster, until it reaches a balance with all the other detrimental genotypes.
The case for the action of selection is based on the following three arguments.
Inferences based on coding data reflect, in large part, the action of selection.
Reasons for this tendency could be genetic drift or the action of selection acting on this sample; however, no action of selection on the IGF-1 locus was evidenced in our study.
