Sentence examples for action its role from inspiring English sources

This review will provide a brief overview of the efflux transporters associated with the intestine and BBB, followed by P-gp efflux transporter's mechanism of action, its role in CNS drug delivery, and current and potential schizophrenia therapy.

In summary, the main findings of this work are the predominance of c-Myc as a target of estrogen action, its specific role as a mediator of estrogen effects on cell growth, and the ability of functionally-based gene signatures to stratify patients treated with tamoxifen into groups with differing outcome, potentially identifying distinct mechanisms of tamoxifen resistance.

Meanwhile, Bank of America profits rose by 11% to $2.4 billion.J.P. Morgan Chase is likely to face legal action for its role in helping Enron to disguise its debts.

DealBook »   Nomura May Face Regulatory Action for Insider Trading  |  Japan's financial services minister said Nomura may face "severe action" for its role in an insider trading case, Bloomberg News reports.

Money & Business called many companies that had filed briefs in support of Michigan, seeking nonwhite executives who might be willing to talk about their views on affirmative action and its role in their careers.

Here, the law is meant to work as a constraint on government's action, and its role as a constraint is claimed to be valuable.

But the LMDC, in an April 2002 articulation of its principles for action, asserted its role in revitalizing lower Manhattan.

A new class action was started on July 6 against Barclays and other Euribor panel banks alleging manipulation, and the bank and a current and former director have been named as defendants in a pending class action for its role as a Libor contributor and alleging mis-statements in past annual reports.

The function of menin is complex, and discovering its mechanism of action and its role in tumorigenesis in the MEN1 syndrome has largely been through the study of its interaction with nuclear and cytosolic proteins.

SGK-1 stimulates a variety of ion channels, transporters and transcription factors, which can modulate kidney function, blood pressure and insulin action, suggesting its role in the pathophysiology of DM and its complications like diabetic kidney disease.

We propose that through this distributive action and its role as a connector/adaptor, Mic19 regulates the copy number of the MICOS complex and, consequently, the copy number and position of cristae junctions.