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The principal (potential) novelty and scientific importance of the current study come from the demonstration of the role of Brahma in intestinal stem cell (ISC) regulation and of mechanisms by which its action is regulated.
In addition, IGF-1 action is regulated via its interaction with multiple binding proteins [ 7, 10].
Bone morphogenetic proteins (BMPs) are expressed during osteogenesis and their action is regulated by corresponding BMP inhibitors.
Their action is regulated by gene expression, pericellular accumulation, biochemical activation and interaction-deactivation with TIMPs, their endogenous inhibitors.
This action is regulated by CD4+ T lymphocytes, IgA and IgE antibodies, antibody-dependent eosinophil cytotoxicity, and the classic complement pathway [ 58].
Glu is the most prevalent excitatory neurotransmitter in the CNS and its action is regulated by two types of receptors: the ionotropic (iGlu) and metabotropic (mGlu) receptors.
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The protein amounts of the different signaling molecules involved in insulin action are regulated by their rates of synthesis and degradation.
Glucocorticoid and androgen action are regulated at a prereceptor level by the enzyme 5α-reductase type 2 (SRD5A2), which inactivates glucocorticoids to their dihydrometabolites and converts T to DHT.
These findings together demonstrate that cyp-35B1 expression under conditions of low daf-2 pathway activity is regulated by coordinate action of daf-16 and hsf-1.
Their actions are regulated by IL-1 receptor antagonist (IL-1ra) and IL-18 binding protein (IL-18bp).
According to social cognitive theory [ 9], human motivations and actions are regulated extensively by forethought.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com