Sentence examples for action has been established from inspiring English sources

Linear low-dose extrapolation from the point of departure to the origin is generally used to estimate low-dose risks for carcinogens, unless a nonlinear mode of action has been established (U.S. EPA 2005).

Maraviroc demonstrates potent antiviral activity against all CCR5-tropic HIV-1 viruses tested (geometric mean 90% inhibitory concentration of 2 nM); its mechanism of action has been established using cell-based assays, where it blocks binding of gp120 to CCR5 to prevent the membrane fusion events necessary for viral entry.

However, this analysis largely considered chemicals for which a mutagenic mode of action has been established and for which a linear, no-threshold dose response function is assumed for the low-dose range being considered for risk assessment, and comparing potencies can be shown to be the same as comparing doses.

Although some mechanisms of NO action have been established, such as its reversible active site inhibition of cytochrome c oxidase, the breadth of protein targets of NO within mitochondria is not well understood.

Loss of consciousness If an anaphylaxis action plan has been established and an Epipen is available, inject it.

The mechanism of the vasodilator action of H2S has been established to be primarily mediated by KATP channels, which can be potentiated by NO.

The International Network for Food and Obesity/non-communicable diseases (NCDs) Research, Monitoring and Action Support (INFORMAS) has been established to reduce obesity, NCDs and their related inequalities globally.

However, unlike many proposed AD risk factors, the mechanism of action for SORLA has been established in numerous studies in cell cultures, in animal models, and even in patients providing a solid base for theoretical simulations.

Because ipilimumab is associated with a set of immune-related adverse events that likely reflect the agent's mechanism of action, a management guide has been established.

In addition, educational practitioners are encouraged to conduct action research, an agenda which has been established by the MOE since 1999.

To date, the applicability of independent action for multi-component mixtures has been established for algae [ 9] and bacteria [ 10], but empirical data demonstrating that the concept is valid in mammalians is missing altogether [ 11].