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Various IRES trans acting factors or ITAFs have been implicated to have role in mediating internal initiation of translation.
Much less is known about trans acting factors that may drive the C4differentiation process [ 18, 19].
Under these conditions a number of paracrine acting factors are locally secreted which stimulate further proliferation of surrounding cells [39].
Others have suggested that this relationship will be maintained for cooperatively acting factors [36].
Transcriptional initiation in eukaryotes is often regulated by multiple cooperatively acting factors.
Tissue repair- is driven by positively and negatively acting factors.
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Trans-acting factors also influence the expression of genes, but they act by intermediary diffusible molecules (proteins, RNAs).
However, the trans-acting factors involved in the regulation of the lncRNA precursors are still unknown.
These parallel-acting cis-regulatory modules are responsive to a multitude of distinct trans-acting factors.
The trans-acting factors responsible for IRES activation during hypoxia are under investigation.
These studies in rice showed the important role of trans-acting factors on asymmetric expression of parent-specific alleles.
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