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When the pathway is activated, the receptor is cleaved and its intracellular region is translocated to the nucleus, acting as a transcription factor in conjunction with the CBF-1 (C promoter binding factor-1) protein.
57, 58 Interestingly, simple heterozygous parkin gene deletion (happloinsufficiency) has also been suggested to be enough in some cases to induce parkinsonism, perhaps acting as a susceptibility or risk factor in conjunction with other genetic or environmental risk factors, but to date this remains an open question.
It will be his task, in conjunction with the governor of the Bank of England, Mark Carney, and David Cameron acting as a caretaker prime minister, to bring a semblance of shape to the chaos that is likely to ensue.
Indeed, as well as acting as a membrane signal transduction receptor, nuclear HER4 is required for mammary gland development and lactation through gene regulation in conjunction with STAT5A [ 11, 12], and mitochondrial HER4 has been shown to mediate apoptosis in the mitochondria via BAK [ 13].
But acting as a planetary sponge has taken a toll.
She is currently acting as a consultant for Communities Crossingg.
It does this by acting as a brake or switch.
Shah is acting as a consultant to the company.
They are acting as a lifestyle brokerage.
My client was acting as a Good Samaritan.
Murphy began acting as a child.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com