VKOR, an essential enzyme in mammalian systems, acts to convert Vitamin K epoxide, formed by Vitamin K carboxylase, to its (initial) quinone form for cellular reuse.
Elovl6 acts to convert C16 saturated and monounsaturated fatty acids to C18 fatty acids and can potentially affect over 50% of the cellular lipidome.
Tamhankar and others have demonstrated that omeprazole does not reduce the number of reflux episodes or their duration, but acts to convert acid reflux to less acid reflux [ 31].
Furthermore, it has been demonstrated that combined adenovirus transfection of wild-type p53 (wt p53) into glioma cells followed with chemotherapy treatment SN-38 may act to convert gliomas to an "apoptosis-sensitive" phenotype [ 8].
This immediately reveals the mechanism for the chameleon transformation: the P56S mutation acts to convert the well-folded cytosolic MSP domain into an unstructured membrane-active protein like mellitin and α-synuclein, by disrupting the specific long-range interaction network that stabilizes the native β-sandwich MSP fold.
Ricin is a lethal poison found naturally in castor beans, but it takes a deliberate act to convert it into a biological weapon.
McCulloch proposed a bill, the Contraction Act, to convert some of the greenbacks from notes redeemable in bonds to interest-bearing notes redeemable in coin.
Despite commercial success, the interest payments on the mortgage were crippling, and in 1846 the company obtained an Act to convert the canal into a railway, although its powers were never used.
In addition, high ammonia concentrations (relative to water) act to convert crystalline cellulose to the more digestible cellulose III [ 24].
It is generally accepted that phosphorylation of Ser518 acts to convert Merlin into a less active state in suppressing cell growth.
These behavioral responses rely crucially on the hypothalamic pituitary adrenal system (HPA axis), which acts to rapidly convert neurally derived perceptual information ("something strange or threatening is here!") to hormonal signals, especially epinephrine ("adrenalin"), released from the NCC-derived adrenal medulla.
