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The phrase "acted on the knowledge" is correct and usable in written English.
You can use it when describing a situation where someone takes action based on information or understanding they have acquired.
Example: "After reviewing the data, the team acted on the knowledge they gained to implement new strategies."
Alternatives: "acted upon the information" or "took action based on the knowledge".
Exact(3)
Neither of those men, though, acted on the knowledge, choosing instead to maintain an unchanged relationship with the children.
He always knew when his body or his mind had had enough and he always acted on the knowledge.
We acted on the knowledge that without an appropriate organizational culture, only small, temporary improvements will be possible [ 23].
Similar(55)
Let's gain the best perspective ever on our current reality: To have the greatest books ever written available at the touch of a button; to be able to operate and run businesses from home near to friends, family, and loved ones; to act on the knowledge of the greatest minds the world has ever seen...these are all happening right now.
"I do think the Obama team knows this and seems prepared to act on the knowledge".
Knowledge management systems provide a means to assemble and act on the knowledge accumulated throughout an organization.
I don't mean, when should we act on the knowledge that life is ending — that is an entirely different problem.
It also involves our learning to act on the knowledge that, as regards our humanity, we are neither superior nor inferior to other people.
Finally, flexibility to act on the knowledge gained through sensitivity is needed to design evolving processes able to contribute to the resolution of complex real-world problems.
"It took me a while to act on the knowledge but I left him".
A precautionary approach to protecting public health requires us to act on the knowledge we do have, and what we know now about environmental toxins is more than enough for the American Cancer Society take a position in favor of public health.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com