They are present in a wide range of eukaryotes including the vast majority of animal cells, and appear to act as organizers not only for the mitotic spindle but also for the interphase microtubule cytoskeleton, thereby playing key role in the positioning and traffic of intracellular organelles.
These proteins act as organizers of membrane-signalling complexes.
Indeed, tip cells act as organizers in primitive multicellular systems; in Dictyostelium, cells at the tip of the "slug" act to guide its migration and to control the differentiation of its constituent cells (Rubin and Robertson, 1975).
Tip cells or groups of cells at the distal tips of outgrowing epithelial tubes act as organizers in tubular systems, from the migrating Dictyostelium slug to the branching epithelial scaffolds of human organs.
From 1910 to 1912 he acted as an organizer for the Social Democratic Party and secretary to the mayor of Milwaukee.
She acted as an organizer for the Save Our Safety Net Campaign immediately before joining CNHED.
The instructor's notes also provided a great guide and acted as an advance organizer (Mayer 1979) for students when they started to read the textbook to decide what content was the most important.
The governor, Yoichi Masuzoe, is the second leader of the Japanese capital's metropolitan government to leave office over a financial scandal in two and a half years, an especially embarrassing development because the city will host the Summer Olympic Games in 2020 and counts on the governor to act as an organizer and global ambassador.
This structure acts as an organizer of the cell aggregate: grafting of exogenous tips onto an aggregate induces the formation of a slug at the site of each tip [7].
Endosomal trafficking acts as an organizer and modulator of many signaling events between and within cells at multiple stages of animal development (for comprehensive reviews, see [ 55, 56]).
Kcnq1ot1/LIT1 acts as an organizer on a tissue/lineage-specific nuclear domain, involving in epigenetic silencing of the Kcnq1 imprinting control region [ 46- 49].
