Sentence examples for act to sensitize from inspiring English sources

These results were obtained at the time when it was already known that PAR3 can act to sensitize PAR4 for thrombin action, implying a proximity of PARs 3 and 4.

Although LCL85 does not effectively sensitize Colon 26 cells to FasL-induced apoptosis, LCL85 is effective in suppressing Colon 26 cell metastatic potential in vivo, suggesting that other host factors, such as IFN-γ and TNFα secreted by T cells, might also act to sensitize the tumor cells to apoptosis in vivo, which requires further study.

Mice lacking cyclophilin D do not undergo cyclosporin A-sensitive permeability transition but still form mPTP at higher matrix Ca2+ concentrations [ 10– 12], indicating that cyclophilin D is not an essential component but may act to sensitize the Ca2+ trigger site of the pore.

This suggests that this tumour-derived lipolytic factor acts to sensitize adipose tissue to lipolytic stimuli, and that this effect is attenuated by EPA, which is known to preserve adipose tissue in cancer cachexia.

They argued that stochastic resonance, which enhances the response of a nonlinear system to weak stimuli, acts to sensitize mechanoreceptors in the target skin area thereby making subthreshold stimuli detectable (Dhruv et al 2002).

Secondly, under visible light irradiation, the S,N-GQDs act as a photosensitizer to sensitize P25 and donate the electrons to the conduction band of P25, leading to the visible-light-driven photocatalytic H2 production activity.

These results suggest that SeC can act as an enhancer to sensitize AF-induced cell growth inhibition against A549 cells by induction of apoptosis.

Redox-directed therapeutics have been developed to act as direct inhibitors of cancer and to sensitize tumors to first-line agents; however, they are associated with significant toxicity.

Proinflammatory molecules act to heal the injured/inflamed area and also to sensitize nociceptive neurons, thus increasing the pain response in order to prevent further insult [ 78].

Finally, we show that not only does FoxO3 act as a TH target, but also that its action is required to sensitize muscle stem cells to TH levels.

cADPR has been shown not only to act on intracellular Ca2+ release via RyR (ryanodine receptor) [ 17], but also to sensitize the TRPM2 cation channel for its ligand ADPR [ 28, 29].