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Genetic manipulation of key transcription factors (TFs), which act to orchestrate production of multiple regeneration-associated genes, has emerged as a promising strategy.
Thus, Shp2 may act to orchestrate hESC/mESC differentiation at least in part through bi-directional regulation of BMP4-Smad signaling in the two types of stem cells.
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In particular, miR-210 is induced in hypoxic cells and acts to orchestrate the adaptation of tumor cells to hypoxia.
This combined but differential CTD phosphorylation is often considered to be a molecular code that acts to orchestrate transcription and coupled pre-mRNA processing.
3′,5′-cyclic adenosine monophosphate (cAMP) is a ubiquitous intracellular second messenger that acts to orchestrate a number of important physiological functions that are triggered by activation of specific cell-surface receptors.
Multiple miRNA target sites within a 3'-UTR suggest that miRNAs act together to orchestrate the modulation of mRNA translation [17], [18], [19], [20], [21].
These proteins localize to centrioles and act in sequence to orchestrate centriole duplication in the worm embryo.
Numerous studies have shown that C and N metabolites are monitored by the cell and act in concert to orchestrate gene expression, thus determining transcript profiles that are appropriate to nutritional and metabolic status [ 21- 23].
In legal papers filed last month, the corporation claimed that nine banks, which also include Deutsche Bank and UBS, acted with the British Bankers Associationn to orchestrate the "sustained and material suppression" of Libor between August 2007 until at least the end of 2009 " in what could become the largest private lawsuit brought over the manipulation of benchmark borrowing rates.
Therefore, we sought to determine whether Lrig3 acts through ErbB pathways to orchestrate canal morphogenesis.
Nevertheless, when high numbers of bacteria are present, TLR2 acts together with TLR4 to orchestrate the immune response, a protective effect that is primarily mediated by hematopoietic cells.
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