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The phrase "act regardless of" is correct and usable in written English.
It can be used when indicating that someone will take action without considering certain factors or conditions.
Example: "She decided to act regardless of the potential consequences."
Alternatives: "act without regard to" or "act without considering".
Exact(33)
Iran does not act regardless of international opinion; it deliberately acts with it in mind.
An innately immoral act, regardless of whether it is forbidden by law.
When the UN identifies crimes such as these it needs to act, regardless of who the perpetrators are".
So are there actors you'd go to see on stage just to see them act, regardless of what they're in?
"We all have to act regardless of whether you think your country is responsible for 00.1% of pollution or 85%.
Rightwing libertarianism recognises few legitimate constraints on the power to act, regardless of the impact on the lives of others.
Similar(27)
This ignores the long history of such acts, regardless of who occupied the Oval Office.
Seeking to understand the source of hate does not equate to condoning hateful acts, regardless of who is committing them.
If the concept of war crimes is ever to mean anything, it will have to be defined as categories of acts, regardless of alleged provocation.
There are so many ways in which the UCI could support the sport for women, but instead they have acted, regardless of their intent, in a way that has caused the sport to lose events.
Institutions of higher education have for years been disciplining students for conduct violations, including criminal acts, regardless of whether the students are defendants in a criminal case".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com