The phrase "act on the same" is not correct in standard written English.
It may be intended to convey the idea of taking action based on a previously mentioned subject, but it lacks clarity and completeness.
Example: "We need to act on the same principles we discussed in our last meeting."
Alternatives: "act accordingly" or "take action on this".
If all mixture constituents act on the same molecular target, it is thought that one chemical can be replaced by an equal fraction of an equi-effective concentration (e.g. an EC50) of another, without diminishing the overall combined effect.
Calculation of a resultant requires that all vectors act on the same object: in concert (when the vectors are acting at the same instance) or serially (when each vector acts at a different instance).
In the autocrine signaling process, molecules act on the same cells that produce them.
Kaplan recalled, "I thought, O.K., if zopiclone and benzodiazepines act on the same brain receptor, why don't I try to make another drug — a hybrid?
It aims to have properties similar to the botulinum toxin and can theoretically act on the same nerve-muscle connection that Botox works on.
They act on the same receptors on our brain cells that respond to nicotine.
The chemicals act on the same systems in the body as other opioids such as heroin and morphine.
Our data also systematically unmasked complex genetic architectures, revealing that multiple closely linked driver mutations frequently act on the same quantitative trait.
The same behaviour has been observed in migraineurs after beta-blockers prophylaxis, showing that different drugs, by modulating separate pathways, may act on the same pathophysiological mechanism.
Comparing the docking poses of the designed derivatives with DJK_3021_A, it could be postulated that the designed compounds might act on the same enzyme target where DJK_3021_A acted.
Regardless of explanations, the model proposed in this study cannot be used to test drug candidates that act on the same level of the migraine cascade as sumatriptan.
