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These results indicate that both, FASN and THRSP, exhibit pleiotropic effects for most fatty acids and act in a coordinate manner to contribute to the formation of fatty acid involved in de novo synthesis.
Rational design of new interventions aimed to slow down this process should act in a coordinate way, targeting pro-aging signals as well as altered cellular communication pathways for the effective prevention of aging-related disorders.
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More links were found in hub genes between modules 1 and 3 than between any other modules, suggesting that the genes in these two modules act in a more coordinate fashion.
The United Nations mission, which lost many leaders and colleagues in the disaster, is working to act in a coordinating role.
However they are heavily dependent on the availability of a genome sequence to act as a coordinate system.
Thus, at C-824T, factor MEF2 acted in a directionally coordinate fashion (at T > C) to explain the in vivo trait associations, whereas at A-581G, factors SP1, AP2, and EGR1 displayed similar differential actions (at G > A).
In summary, our study demonstrates that a ubiquitin ligase and a DUB can act in concert to coordinate protein turnover at the ER by regulating the ubiquitination status of a degradation machinery factor.
These genes act in a common pathway, coordinating the removal of failing mitochondria via mitophagy.
These important adaptive responses whereby fibrosis and inflammation act in coordinate manners may provide additional insight into the tumor promoting nature of the reactive stroma microenvironment observed in most carcinomas [3].
These physical factors are ubiquitous in the physiological setting and can act in synergy to coordinate migration of fibroblastic cells.
Considering that the architectural arrangement of blood vessels in the adrenal cortex is such that nearly every adrenocortical cell is thought to lie adjacent to a vascular endothelial cell (39), SF-1-dependent Ang2 expression in adrenocortical cells could be postulated to act in a paracrine way and coordinate vascular remodeling in the developing adrenal.
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CEO of Professional Science Editing for Scientists @ prosciediting.com