Sentence examples for act as suppressor from inspiring English sources

Previous in vitro studies in cell lines derived from advanced PCa suggested that PTEN could act as suppressor of AR activity [ 31, 32].

Among these 24 deficiencies, our results show that deficiencies uncovering the polo locus act as suppressor of bubR1 nondisjunction by delaying meiotic prophase I progression and restoring chiasmata formation as observed by the loading of the condensin subunit SMC2.

However, in extension of the findings by Chen et al., [ 9] we further observed that AhR in the same cell type may also possess anti-inflammatory properties, and we propose that whether AhR act as suppressor or inducer of inflammation largely depends on the type and combination of stimuli.

To establish the functional capacity of in vitro-differentiated FOXP3mut Tr1 cells to act as suppressor cells, we tested whether naïve T cells from IPEX patients differentiated in Tr1-polarizing conditions could suppress the proliferation of allogeneic CD4+ T cells as efficiently as HD Tr1 cells.

Also, second-site mutations at other genes can act as suppressors, restoring wild type function.

We conclude that JNK1 and JNK2 can act as suppressors of mammary tumor development.

The assumption here is that miRNAs primarily act as suppressors of mRNA during development.

This is particularly interesting as mutants lacking the C-terminus of JIL-1 act as suppressors of position effect variegation [27].

In budding yeast, Rho3 was isolated as a suppressor of the cold-sensitive Rab GTPase mutant, sec4-P48, and 4 distinct components of the exocytic machinery, Sec4, Sec9, Sro7, and Sso2, can act as suppressors of rho3 deletion mutants [4].

As mentioned above, these findings revealed that miRNAs act as suppressors of cell-autonomous metastatic phenotypes.

In this regard, it is worthwhile to mention that potyviruses encode proteins that act as suppressors of PTGS [ 34].