The phrase "act as il" is not correct in written English and does not convey a clear meaning.
It seems to be a typographical error or an incomplete thought.
Example: "You can act as if you are the leader in this project."
Alternatives: "function as if" or "serve as though".
Other cells such as neutrophils can act as IL-6 reservoirs, and it is likely that the fibroblast is not the only source of IL-6.
The recombinant sIL-11Rα in vitro acts as IL-11 agonist [ 10- 12].
It has recently been shown that Treg cells can act as an IL-2 'sponge', competitively depriving adjacent T-cells of autocrine IL-2, and thus preventing the IL-2-dependent processes of T-cell activation and proliferation (de la Rosa et al., 2004; Scheffold et al., 2005).
For instance, the effector T cells may be killed by Tregs through granzyme and perforin-mediated cytolysis [ 40, 41]; while during the activation phase, the Tregs may consume the IL-2 cytokine present in the environment and act as an IL-2 "sink" [ 42], or negatively regulate the interaction of Tconv with DCs [ 43], thus preventing a productive, complete T cell activation.
Furthermore, sIL-11Rα can act as an IL-11 antagonist when tested on cells expressing the membrane IL-11Rα and gp130 [ 11].
Given that STAT6 has been demonstrated to act as an IL-4 signal mediator (Sajic et al., 2013), we thus first examined the impact of Cx3cr1 deficiency on the STAT6-PPAR-γ axis, an essential signaling pathway relevant to the induction of M2 macrophages (Sica and Mantovani, 2012).
Because IL-22R1 can combine not only with IL-10R2 to act as a functional IL-22R complex but can also interact with IL-20R2 to form a receptor for IL-20 and IL-24 [ 32], it is likely that IL-22R1 ligands other than IL-22 may play a role in ameliorating HFD-induced metabolic syndrome.
To act as efficient porogens, ILs have to possess: (i) high boiling temperature to avoid any premature evaporation, (ii) high thermal stability to remain unchanged up to the complete curing of the polymer networks, and (iii) easy extractability to be readily removed from the cured networks, thus affording porous thermosetting materials.
Thorpe et al [48] showed that verotoxins act as mediators of IL-8 secretion by intestinal cells.
NO regulates chondrocyte and cartilage functions and often acts as an IL-1β second messenger.
As a result Treg do not produce IL-2, and even may act as a 'sink' for IL-2.
