Sentence examples for act as checkpoints from inspiring English sources

Levels are made up of a series of large "rooms" rather than the single long corridors typical of platformers at the time and the doors between these rooms act as checkpoints returning the player to the beginning of a "room" when they die rather than starting the level over.

Under normal conditions, proliferation is tightly regulated through the action of cyclins, cyclin dependent kinases (CDKs), and CDK inhibitors which regulate the transitions from G1 to S phase and G2 to mitosis and act as checkpoints to prevent replication if DNA is damaged [8].

Lymphatic vessels have many lymph nodes, which act as checkpoints for the immune response.

The cell cycle is a tightly regulated process, with each step carefully monitored by a specific group of proteins that act as checkpoints for proper cell division.

The outcome of this analysis was the percentage of methylated cytosines (%mC) in the promoter regions of two tumor suppressor genes (p16 and p53) that act as checkpoints in the cell cycle, and in two repetitive elements [LINE-1 (long interspersed nucleotide elements) and Alu (short interspersed elements)].

The most promising immune-based treatments are monoclonal antibodies that act as checkpoint inhibitors (e.g., ipilimumab and nivolumab), adoptive cell therapy (e.g., T cells expressing chimeric antigen receptors), and vaccines (e.g., Sipuleucel-T).

It now appears that immune targeting of mutated "neoantigens" plays a major role in successful ACT, as well as in other immunotherapies such as checkpoint inhibitors.

Act as much as possible.

Act as quickly as possible.

In addition, due to the oncogenic potential of the reprogramming factors and the reprogramming-induced DNA damage, the critical tumor suppressor pathways such as p53 and ARF are activated to act as the checkpoints that suppress induced pluripotency.

This idea was proposed by Thorpe et al. (1998), who suggested that growth thresholds act as developmental checkpoints in early life history stages to signal future life history tactics.