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The most unique and significant property of it is revealed in its ability to act as a sequence specific DNA binding factor.
Cas1 therefore might be expected to act as a sequence specific integrase, although local DNA structure could also play a part.
Whether this reflects a mechanism of phase variation is unlikely, but silent drp genes may act as a sequence reservoir for the emergence of new Drp expression patterns.
Bcl6 is a zinc finger protein known to act as a sequence specific transcriptional repressor; it plays an important role in the maturation of B-cells and high Bcl6 expression is considered to be of favourable prognostic value [ 38, 39].
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TP63, which is the most significantly enriched motif in HSEL compared to MSEL, is known to act as a sequence-specific DNA binding transcriptional activator or repressor.
The p53 tumor suppressor can act as a sequence-specific transcription factor that regulates target gene transcription and expression to modulate various cellular processes.
Additionally, it has been demonstrated that dimethyl-DAPP2+ can be used as a selective fluorophore to detect A- and T-rich single-stranded polynucleotides, as well as having the potential to act as a sequence-specific artificial photonuclease.
PRDM5 acts as a sequence specific DNA-binding transcription factor, and its consensus DNA binding sequence has recently been described [15].
It is probable that the coding sequence of a gene may act as a regulatory sequence for its neighboring genes.
Acting as a sequence-specific endoribonuclease, it cleaves single-stranded RNA substrates with concomitant addition of guanosine.
R.PabI is an exceptional restriction enzyme that acts as a sequence-specific DNA glycosylase.
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