Moreover, myod1 has recently been reported to be a direct target of Gli2 in mammalian cells (Voronova et al., 2013) and a GBR has been identified downstream of the prdm1 gene in mouse and shown to act as a Shh responsive limb specific enhancer (Vokes et al., 2008).
FGL2 has been shown to act as an immune responsive coagulant in settings such as foetal loss driven by Th1 polarized immune responses [ 64] and fulminant hepatitis [ 65].
Histone deacetylase-9 has been shown to act as a signal-responsive repressor of cardiac hypertrophy (Zhang et al, 2002).
TLP3 is believed to act as a stress-responsive plasma membrane-tethered transcription factor [ 51] and in plants acts in both stress responses and reactive oxygen species (ROS) signaling [ 52].
Consequently, activity-dependent plasticity may be implicated, and interestingly TDP-43 has been shown to act as an activity-responsive factor that represses translation in the dendrites of hippocampal neurons [ 39].
While GLUT8 has been reported to act as an insulin-responsive GLUT isoform in murine blastocysts [ 15], in other many mammalian cell types GLUT8 localizes primarily to lysosomal compartments and does not translocate to the cell surface in response to insulin.
The thyroid is not known to act as a traditional estrogen responsive tissue such as breast.
GLUT12 is currently hypothesized to act as a second insulin-responsive GLUT in addition to GLUT4.
Its core function is to act as a wise, well-informed, responsive and responsible agent of the Scottish people in identifying that excellence, and in providing funds to support it.
These results suggest that Mut6 acts as a stimulus-responsive nanocapsule.
