Sentence examples for across the endpoints from inspiring English sources

The method for building composites was the O'Brien global statistic which is the average of the standard z-scores across the endpoints.

Another potentially useful approach in exploratory studies where the most sensitive endpoint to the therapy is unknown is to analyse multiple endpoints individually and look for consistency of results across the endpoints.

In order to strongly control the type-1 error at 2.5%% 1-sided, a multiple testing procedure with an alpha-exhaustive recycling strategy [ 39] will also be employed across the primary endpoint PFS and secondary endpoints ORR and OS.

Secondly, a tendency to a dose response pattern was apparent for sumatriptan, eletriptan, and rizatriptan across the different endpoints.

The principle of minimum paths across the computed endpoints was reloaded at the statistical level of only correlation factors, leading to a complete ergodic-hierarchical framework that permits the identification of the structural dynamics triggering carcinogenesis.

However, when there is a gradient of importance across the individual endpoints, it may be invalid to combine them in the form of a composite.

This study was not powered to formally compare FF with FP; furthermore, no consistent trend was observed in any treatment group across the remaining endpoints.

O'Brien [ 11] suggested a global rank-sum-type test, based on a simple or weighted sum of ranks across the individual endpoints.

Despite these limitations, the consistent trends observed across the four endpoints support that etoricoxib, as an example of an NSAID, provides symptomatic efficacy in RA patients in the presence of concomitant treatment with bDMARDs and/or CS.

We first pooled the individual city time-series and case-crossover study estimates across the stroke endpoints, generating a pooled estimate (risk ratio) of 1.007 955% confidence interval = 1.003 1.01).

In each situation, one has the added value of placing exposure disease relation into a broader public health context by potentially weighing risks and benefits across the multiple endpoints.