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Unfortunately, several problems in interpreting across studies were identified, including lack of a universal social skills definition, differences in levels of intensity or duration of social skills training, differences in services provided in the clinic or classroom.
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Themes across these studies were identified and compared.
A total of ten primary studies were identified across five systematic reviews.
Twenty-one studies were identified across ten countries, including one European-wide study, which explicitly reported IFD-related or attributable mortality.
Figures 3, 4 and 5 respectively present the prevalence for school students, university students and adults across countries for which published studies were identified.
Nine studies were identified, with results published across 13 included publications, which had mostly low to unclear risk of bias.
No case-control studies were identified.
Relevant studies were identified through MEDLINE searches.
Although, only 11 studies were identified, age at diagnosis and time to insulin were consistent as discriminatory criteria across studies.
A majority of studies reported significant differences in at least one adherence measure between the study groups (19.7 % significant differences vs. 8.5 % non-significant differences), but a potential publication bias across the studies was identified through the funnel plot.
Whilst a trend was identified towards a delay in onset of VMO relative to the VL in the AKP population during both voluntary active tasks and reflex activity, a substantial degree of heterogeneity across the pooled studies was identified (I2 = 69.9 93.4%, p < 0.01).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com