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In the case of acidocalcisome/volutin granule organelles, it seems plausible to suggest a deep evolutionary origin, given the presence of both the H+PPases and these organelles across representatives from all three domains of life.

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Our analysis of phosphatase activity using both a generic substrate and a panel of phosphopeptides represents a large set of comparable data across representative PTPs.

Across representative species, we discovered that recently evolved enhancers are significantly over-represented in the vicinity of positively-selected genes and can often suggest candidate regulatory elements that could mediate species-specific adaptations.

Spectra integrated across representative ROIs are shown in Figure 3D,F.

From 2005 to 2010, annual monitoring campaigns were conducted by the Centre for Mined Land Rehabilitation of The University of Queensland across representative rehabilitated landscapes located within the Amity, Bayside, Ibis, and Gordon mining areas (Figure 1) collectively spanning 4 20 years post-rehabilitation (Table 1).

To gain novel insights into the evolutionary perspective on the structure and function relationships of STIMs, I unitized two complementary approaches: (1) mapping potentially critical residues by sequence alignments of STIM structural domains across representative species; (2) detecting phylogeny-based site-specific evolutionary rate changes with the program DIVERGE [31].

It highlights significant variation in prevalence across representative groups and provides compelling evidence that AKI is strongly linked with CKD burden.

Fourth, the size of the population was extremely large thereby allowing us generate very precise estimates of CKD across representative subgroups.

In total, the NMR experiments described here suggest that DD2, compound 2, and compound 3 bind the dimer interface across representative members of all HHV Pr subfamilies.

To determine whether TUD patterns are conserved, we measured TUD profiles across representative bacteriophage genomes, comparing each portion tested against the genome mean [ 24].

An average intratumoural TIL score/high-power field ( × 400) was calculated across representative areas of each triplicate core to allow for intratumoural heterogeneity (i.e., an average of three counts across the tumour).

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