Sentence examples for across multiple indications from inspiring English sources

To describe the use of systematic reviews or overviews (systematic reviews of systematic reviews) to synthesize quantitative evidence of intervention effects across multiple indications (multiple-indication reviews) and to highlight issues pertaining to such reviews.

In the original report published on the CTC-chip, the authors reported an average CTC count of >50 CTC/ml and that 100% of patients across multiple indications showed >5 CTCs/mL of blood [26], a significantly higher prevalence and number than are typically described for the CellSearch® platform [18].

These topics are usually focused on drug therapy, and often are constrained to a particular class of drugs across multiple indications.

The overall safety data for 4 years of adalimumab therapy for CD were consistent with long-term safety data representing nearly 12 years of adalimumab exposure across multiple indications.

In this study, the reported risk ratio (95 % CI) for serious infection in patients exposed to tofacitinib in randomized controlled trials (across multiple indications) was 1.57 (0.65, 3.82), in line with the present analysis.

The development of apixaban reflects a strategy to optimize the clinical pharmacology profile, dosing posology, trial designs, and statistical analyses across multiple indications, and to seek alignment with global health authorities.

Accordingly, the knowledge that the IR-A/IR-B mRNA ratio is altered across multiple cancer indications is the foundation for continued efforts to characterize the effect of this alteration on cancer progression and therapeutic response in order to achieve the most benefit.

Although Mcl-1 has emerged as a significant cancer cell survival and therapy resistance factor across multiple cancer indications, it is now widely recognized that capturing the therapeutic benefit of Mcl-1 antagonism will likely rely on rational synthetic lethal strategies [ 1].

Many of the biologicals are approved for multiple indications, but it is not always possible to extrapolate across indications for the corresponding biosimilars.

Primary indications for boluses (n = 93) given to study patients were: hypotension (69%); oliguria (15%); and tachycardia (14%), with multiple indications per bolus.

Doxil, a liposomal formulation of the chemotherapeutic drug doxorubicin, is FDA-approved for multiple indications.