Incorporating the similarity between drugs and between targets to infer the interaction of untested drug target pairs is the essence of the read-across methodology [2].
The suggested SEURAT-1 read-across methodology could also be linked with the more formalized approach already implemented into the OECD QSAR Toolbox.
We additionally argue that objectivity in empirical studies of design can be obtained only by triangulating observations across methodologies that embrace both ethnographic and laboratory-based traditions.
Strikingly, the 3 regions showing positive correlations between CT and CSA asymmetries were those known to exhibit robust asymmetries across methodologies, such as the leftward asymmetrical planum temporale and the rightward asymmetrical superior temporal sulcus and cingulate cortex.
"The inconsistencies across methodologies and venders and the cacophony of numbers in the marketplace are clearly confusing," said Sherrill Mane, a senior vice president of the Interactive Advertising Bureau, a trade group that has been advocating for greater accountability in online measurement.
To examine and clarify this we presented a framework to interpret experimental results from across methodologies and have shown how it can lead to insightful interpretations.
Quality control efforts in veterinary laboratories have often observed large discrepancies across methodologies for analysis of proteins, which may be expected for creatinine.
However, prior to testing these parameters, we established a set of output measures to allow us to compare across methodologies and experimental conditions.
Results from this project will be published in international and national peer-reviewed journals, separately and in concluding papers combining data across methodologies.
If there is homogeneity within drugs and across drugs, and the ITC evidence is consistent across methodologies or with DTC evidence, then the ITC evidence in considered strong and free of bias [ 19].
Convergence of the results is confirmed when results of both qualitative and quantitative inquiries results support a hypothesis of the MTHP framework, i.e. when the results are consistent across methodologies.
