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In contrast to the two-loop model, the robustness analysis demonstrated that the model is extremely sensitive to a specific minor group of parameters, which are generally conserved across all reference parameter sets.
Here, across all reference panel types, the discordance rates decreased slightly with increasing marker density s.
We observed that as the panel size k increased, discordance rates decreased across all reference panel types.
When 2003 and 2004 dataset scores were combined, GAPDH (m) ranked highest across all reference genes, followed by actin, EF1-α, and SAND.
Across all reference panel sizes, imputations with the most diverse reference panels consistently provide lower discordance rates than do imputations with the randomly selected reference panels.
Exon capture and high-throughput sequencing identified thousands of putative SNPs spread evenly across all reference chromosomes, in all three individuals, including hundreds of SNPs in our targeted candidate genes.
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We define the likelihood of the i th gene of WH8102, LH i, having orthologs across all the reference genomes as, with p j = m j/n if the gene has an ortholog in the j th reference genome and p j = 1 − m j/n otherwise.
For each atom pair, the minimum and the maximum distances observed across all the reference structures are compared with the distance between the corresponding atoms in the model M being evaluated.
In case of the lDDT, the following approach allows to evaluate a model simultaneously against an ensemble of reference structures: for each pair of atoms, we define an acceptable distance range by taking the minimal and maximal distance observed across all references where the atoms are present.
20 However, both CY and ZN staining techniques have higher specificities compared with FM and PiLED across all the three reference (gold) standards used.
The mean Ct value of all reference genes across all samples ("global mean Ct") was subtracted from the mean Ct value of all reference genes within each sample ("sample reference mean") to determine a normalization factor for each sample.
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