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The caveat here is that the acquisition of the collateral sensitivity mechanism is specific to hematologic-derived cell lines.
These successes did not sit well with John of Bohemia, who refused to be pacified either by the donation of Upper Lusatia in 1320 or by the marriage of Duke Henry the Elder of Lower Bavaria with a Luxembourg the following year, or by the acquisition, by way of collateral, of the Egerland.
Moreover, correct timing of the first-pass acquisition is problematic in patients with severe stenoses and an extensive network of collateral arteries, whose filling occurs very slowly and varies considerably among and within patients [8], [9].
Taken together, these examples illustrate the link of collateral sensitivity to the complex genetic or transcriptional alterations that occur in parallel during the acquisition of the MDR phenotype.
They use the excuse of collateral damage".
Lack of collateral was invariably the reason.
"There's a lot of collateral damage".
"The amount of collateral damage is huge.
Fourth, inspections are a valuable source of collateral intelligence.
"It comes with a lot of collateral damage.
And this, too, brings its own kind of collateral damage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com