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The long term colonization of CF airways selects pathoadaptive variants with several features which differentiate late P. aeruginosa isolates from the initially acquired strain [7], [8].
Also, the IgM antibodies may have been elicited by Msg that underwent antigenic variation in an already acquired strain of P. jirovecii.
Pseudomonas aeruginosa can establish life-long airways chronic infection in patients with cystic fibrosis (CF) with pathogenic variants distinguished from initially acquired strain.
As the disease progresses, P. aeruginosa pathoadaptive variants are distinguished from the initially acquired strain.
Similarly, it was impossible to know whether infection was due to the same strain as that of the colonization or to a newly acquired strain.
Long-term colonization of the CF host is maintained by P. aeruginosa pathoadaptive lineages, which are clonal with the initially acquired strain and carry phenotypic variants.
Similar(51)
The relevant genotypes of the acquired strains were proved by PCR analyses.
This program shows the estimated deformations and plots of the acquired strains, as well as displaying an emergency indicator when necessary, all through post-processing of the strains.
In this post-processing algorithm, the method of least squares was used to determine the difference between the FEA results and the acquired strains.
Most notably, S. pyogenes is a unique species which has acquired strain-specific virulence genes by means of multiple prophages [28], [29].
Furthermore, the incidence of community acquired strains of MRSA has markedly increased over the past several years [5].
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